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A fiber-modified adenovirus co-expressing HSV-TK and Coli.NTR enhances antitumor activities in breast cancer cells

Breast cancers especially in late and metastatic stages remain refractory to treatment despite advances in surgical techniques and chemotherapy. Suicide gene therapy based on adenoviral technology will be promising strategies for such advanced diseases. We previously showed that co-expression of her...

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Bibliographic Details
Main Authors: Zhan, Yang, Yu, Bin, Wang, Zhen, Zhang, Yu, Zhang, Hai-Hong, Wu, Hao, Feng, Xiao, Geng, Ran-Shen, Kong, Wei, Yu, Xiang-Hui
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097267/
https://ncbi.nlm.nih.gov/pubmed/25031704
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