THE GLYCOLYTIC ENZYME, GPI-1, IS A FUNCTIONALLY CONSERVED MODIFIER OF DOPAMINERIGIC NEURODEGENERATION IN PARKINSON’S MODELS([GC1])

Neurodegenerative diseases represent an increasing burden in our aging society, yet the underlying metabolic factors influencing onset and progression remain poorly defined. The relationship between impaired IGF-1/insulin-like signaling (IIS) and lifespan extension represents an opportunity to inves...

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Detalhes bibliográficos
Main Authors: Knight, Adam L., Yan, Xiaohui, Hamamichi, Shusei, Ajjuri, Rami R., Mazzulli, Joseph R., Zhang, Mike W., Daigle, J. Gavin, Zhang, Siyuan, Borom, Akeem R., Roberts, Lindsay R., Lee, S. Kyle, DeLeon, Susan M., Viollet-Djelassi, Coralie, Krainc, Dimitri, O’Donnell, Janis M., Caldwell, Kim A., Caldwell, Guy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097176/
https://ncbi.nlm.nih.gov/pubmed/24882066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.04.017
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