Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice

OBJECTIVE: The liver is the key organ involved in systemic inflammation, but the relation between hepatic inflammation and atherogenesis is poorly understood. Since nuclear factor-κB (NF-κB) is a central regulator of inflammatory processes, we hypothesized that chronically enhanced hepatic NF-κB act...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wong, Man C., van Diepen, Janna A., Hu, Lihui, Guigas, Bruno, de Boer, Hetty C., van Puijvelde, Gijs H., Kuiper, Johan, van Zonneveld, Anton J., Shoelson, Steven E., Voshol, Peter J., Romijn, Johannes A., Havekes, Louis M., Tamsma, Jouke T., Rensen, Patrick C.N., Hiemstra, Pieter S., Berbée, Jimmy F.P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097174/
https://ncbi.nlm.nih.gov/pubmed/21798539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2011.06.055
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