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Motor Function Deficits Following Chronic Prenatal Ethanol Exposure are Linked to Impairments in Insulin/IGF, Notch and Wnt Signaling in the Cerebellum

BACKGROUND: Fetal alcohol spectrum disorder (FASD) is associated with deficits in cerebellar function that can persist through adolescence. Previous studies demonstrated striking inhibition of insulin and insulin-like growth factor (IGF) signaling in ethanol-exposed cerebella. OBJECTIVES: We sought...

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Detalhes bibliográficos
Main Authors: Tong, Ming, Ziplow, Jason, Chen, William Cy, Nguyen, Quynh-Giao, Kim, Charles, de la Monte, Suzanne M
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096945/
https://ncbi.nlm.nih.gov/pubmed/25035811
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