Identification and characterization of ALK kinase splicing isoforms in non-small-cell lung cancer

PURPOSE: Anaplastic lymphoma kinase (ALK) rearrangements are present in an important subset of non-small-cell lung cancer (NSCLC) and predict for response to the tyrosine kinase inhibitor crizotinib. In this study, we evaluated the yet unknown frequency and functional role of ALK splicing isoforms i...

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Autores principales: de Figueiredo-Pontes, Lorena Lobo, Wong, Daisy Wing-Sze, Tin, Vick Pui-Chi, Chung, Lap-Ping, Yasuda, Hiroyuki, Yamaguchi, Norihiro, Nakayama, Sohei, Jänne, Pasi Antero, Wong, Maria Pik, Kobayashi, Susumu Soeda, Costa, Daniel Botelho
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096850/
https://ncbi.nlm.nih.gov/pubmed/24419423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000050
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