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Pitfalls of predicting complex traits from SNPs

The success of genome-wide association studies has led to increasing interest in making predictions of complex trait phenotypes including disease from genotype data. Rigorous assessment of the value of predictors is critical before implementation. Here we discuss some of the limitations and pitfalls...

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Detalhes bibliográficos
Main Authors: Wray, Naomi R., Yang, Jian, Hayes, Ben J., Price, Alkes L., Goddard, Mike E., Visscher, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096801/
https://ncbi.nlm.nih.gov/pubmed/23774735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3457
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