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Pitfalls of predicting complex traits from SNPs

The success of genome-wide association studies has led to increasing interest in making predictions of complex trait phenotypes including disease from genotype data. Rigorous assessment of the value of predictors is critical before implementation. Here we discuss some of the limitations and pitfalls...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wray, Naomi R., Yang, Jian, Hayes, Ben J., Price, Alkes L., Goddard, Mike E., Visscher, Peter M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096801/
https://ncbi.nlm.nih.gov/pubmed/23774735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3457
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