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Effect of Age on Regulation of Human Osteoclast Differentiation

Human skeletal aging is characterized as a gradual loss of bone mass due to an excess of bone resorption not balanced by new bone formation. Using human marrow cells, we tested the hypothesis that there is an age-dependent increase in osteoclastogenesis due to intrinsic changes in regulatory factors...

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Autors principals: Chung, Ping-Lin, Zhou, Shuanhu, Eslami, Behnam, Shen, Longxiang, LeBoff, Meryl S., Glowacki, Julie
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096781/
https://ncbi.nlm.nih.gov/pubmed/24700654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24792
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