Age-Related Intrinsic Changes in Human Bone Marrow-Derived Mesenchymal Stem Cells and Their Differentiation to Osteoblasts

In vivo and in vitro studies indicate that a sub-population of human marrow-derived stromal cells (MSCs, a.k.a. mesenchymal stem cells) has potential to differentiate into multiple cell types, including osteoblasts. In this study, we tested the hypotheses that there are intrinsic effects of age in h...

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Main Authors: Zhou, Shuanhu, Greenberger, Joel S., Epperly, Michael W., Goff, Julie P., Adler, Carolyn, LeBoff, Meryl S., Glowacki, Julie
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2398731/
https://ncbi.nlm.nih.gov/pubmed/18248663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2008.00377.x
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