PI3K/Akt pathway restricts epithelial adhesion of Dr(+) Escherichia coli by down-regulating the expression of Decay Accelerating Factor (DAF)

The urogenital microbial infection in pregnancy is an important cause of maternal and neonatal morbidity and mortality. Uropathogenic Escherichia coli strains which express Dr fimbriae (Dr+) are associated with unique gestational virulence and they utilize cell surface decay accelerating factor (DAF...

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Main Authors: Banadakoppa, Manu, Goluszko, Pawel, Liebenthal, Daniel, Nowicki, Bogdan J., Nowicki, Stella, Yallampalli, Chandra
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096773/
https://ncbi.nlm.nih.gov/pubmed/24599886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214522183
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