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PI3K/Akt pathway restricts epithelial adhesion of Dr(+) Escherichia coli by down-regulating the expression of Decay Accelerating Factor (DAF)

The urogenital microbial infection in pregnancy is an important cause of maternal and neonatal morbidity and mortality. Uropathogenic Escherichia coli strains which express Dr fimbriae (Dr+) are associated with unique gestational virulence and they utilize cell surface decay accelerating factor (DAF...

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Detalhes bibliográficos
Main Authors: Banadakoppa, Manu, Goluszko, Pawel, Liebenthal, Daniel, Nowicki, Bogdan J., Nowicki, Stella, Yallampalli, Chandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096773/
https://ncbi.nlm.nih.gov/pubmed/24599886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214522183
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