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Both Canonical and Non-Canonical Wnt Signaling Independently Promote Stem Cell Growth in Mammospheres

The characterization of mammary stem cells, and signals that regulate their behavior, is of central importance in understanding developmental changes in the mammary gland and possibly for targeting stem-like cells in breast cancer. The canonical Wnt/β-catenin pathway is a signaling mechanism associa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Many, Alexander M., Brown, Anthony M. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096729/
https://ncbi.nlm.nih.gov/pubmed/25019931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101800
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