Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis

The primary cilium originates from the mother centriole and participates in critical functions during organogenesis. Defects in cilia biogenesis or function lead to pleiotropic phenotypes. Mutations in centrosome-cilia gene CC2D2A result in Meckel and Joubert syndromes. Here we generate a Cc2d2a(-/-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Veleri, Shobi, Manjunath, Souparnika H., Fariss, Robert N., May-Simera, Helen, Brooks, Matthew, Foskett, Trevor A., Gao, Chun, Longo, Teresa A., Liu, Pinghu, Nagashima, Kunio, Rachel, Rivka A., Li, Tiansen, Dong, Lijin, Swaroop, Anand
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096663/
https://ncbi.nlm.nih.gov/pubmed/24947469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5207
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados