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Cholesterol-induced activation of TRPM7 regulate cell proliferation, migration, and viability of human prostate cells

Cholesterol has been shown to promote cell proliferation/migration in many cells; however the mechanism(s) have not yet been fully identified. Here we demonstrate that cholesterol increases Ca(2+) entry via the TRPM7 channel, which promoted proliferation of prostate cells by inducing activation of t...

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Detalhes bibliográficos
Main Authors: Sun, Yuyang, Sukumaran, Pramod, Varma, Archana, Derry, Susan, Sahmoun, Abe E, Singh, Brij B
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096426/
https://ncbi.nlm.nih.gov/pubmed/24769209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.04.019
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