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Cholesterol-induced activation of TRPM7 regulate cell proliferation, migration, and viability of human prostate cells
Cholesterol has been shown to promote cell proliferation/migration in many cells; however the mechanism(s) have not yet been fully identified. Here we demonstrate that cholesterol increases Ca(2+) entry via the TRPM7 channel, which promoted proliferation of prostate cells by inducing activation of t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096426/ https://ncbi.nlm.nih.gov/pubmed/24769209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.04.019 |
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