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Angiotensin 1-7 Reduces Mortality and Rupture of Intracranial Aneurysms in Mice

Angiotensin II (Ang-II) stimulates vascular inflammation, oxidative stress, and formation and rupture of intracranial aneurysms in mice. Because angiotensin 1-7 (Ang-1-7) acts on Mas receptors and generally counteracts deleterious effects of Ang-II, we tested the hypothesis that Ang-1-7 attenuates f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Peña Silva, Ricardo A., Kung, David K, Mitchell, Ian J, Alenina, Natalia, Bader, Michael, Santos, Robson A.S., Faraci, Frank M., Heistad, Donald D, Hasan, David M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096422/
https://ncbi.nlm.nih.gov/pubmed/24799613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03415
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