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Pleiotropic Mutations Are Subject to Strong Stabilizing Selection

The assumption that pleiotropic mutations are more deleterious than mutations with more restricted phenotypic effects is an important premise in models of evolution. However, empirical evidence supporting this assumption is limited. Here, we estimated the strength of stabilizing selection on mutatio...

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Bibliografiset tiedot
Päätekijät: McGuigan, Katrina, Collet, Julie M., Allen, Scott L., Chenoweth, Stephen F., Blows, Mark W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Genetics Society of America 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096360/
https://ncbi.nlm.nih.gov/pubmed/24793289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.165720
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