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Pleiotropic Mutations Are Subject to Strong Stabilizing Selection
The assumption that pleiotropic mutations are more deleterious than mutations with more restricted phenotypic effects is an important premise in models of evolution. However, empirical evidence supporting this assumption is limited. Here, we estimated the strength of stabilizing selection on mutatio...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Genetics Society of America
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096360/ https://ncbi.nlm.nih.gov/pubmed/24793289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.165720 |
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