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Redox-Neutral α-Sulfenylation of Secondary Amines: Ring-Fused N,S-Acetals

[Image: see text] Secondary amines react with thiosalicylaldehydes in the presence of catalytic amounts of acetic acid to generate ring-fused N,S-acetals in redox-neutral fashion. A broad range of amines undergo α-sulfenylation, including challenging substrates such morpholine, thiomorpholine, and p...

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Detalhes bibliográficos
Main Authors: Jarvis, Claire L., Richers, Matthew T., Breugst, Martin, Houk, K. N., Seidel, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096192/
https://ncbi.nlm.nih.gov/pubmed/24927364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol501509b
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