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Regulatory factor X1 is a new tumor suppressive transcription factor that acts via direct downregulation of CD44 in glioblastoma

BACKGROUND: The biological functions of regulatory factor (RF)X1, a transcription factor, are not known. Since the RFX1 gene is often epigenetically silenced and clusters of differentiation (CD)44 proteins that regulate cancer cell biology are increased in human glioblastomas, we designed this study...

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Main Authors: Feng, Chenzhuo, Zhang, Ying, Yin, Jinbo, Li, Jun, Abounader, Roger, Zuo, Zhiyi
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096175/
https://ncbi.nlm.nih.gov/pubmed/24526308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou010
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