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Knockout of the regulatory factor X1 gene leads to early embryonic lethality

The biological function of regulatory factor X1 (RFX1), the prototype member of the transcription factor RFX family, is not clear. We have used gene trap technique to disrupt the expression of RFX1 in mice. Although heterozygous RFX1(WT/GT) mice appear normal and fertile, homozygous RFX1(GT/GT) embr...

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Detaylı Bibliyografya
Asıl Yazarlar: Feng, Chenzhuo, Xu, Wenhao, Zuo, Zhiyi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745335/
https://ncbi.nlm.nih.gov/pubmed/19559676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.06.111
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