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Knockout of the regulatory factor X1 gene leads to early embryonic lethality
The biological function of regulatory factor X1 (RFX1), the prototype member of the transcription factor RFX family, is not clear. We have used gene trap technique to disrupt the expression of RFX1 in mice. Although heterozygous RFX1(WT/GT) mice appear normal and fertile, homozygous RFX1(GT/GT) embr...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745335/ https://ncbi.nlm.nih.gov/pubmed/19559676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.06.111 |
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