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Ependymoma stem cells are highly sensitive to temozolomide in vitro and in orthotopic models
BACKGROUND: Ependymoma management remains challenging because of the inherent chemoresistance of this tumor. To determine whether ependymoma stem cells (SCs) might contribute to therapy resistance, we investigated the sensitivity of ependymoma SCs to temozolomide and etoposide. METHODS: The efficaci...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096174/ https://ncbi.nlm.nih.gov/pubmed/24526307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou008 |
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