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Megakaryocytes contribute to the bone marrow-matrix environment by expressing fibronectin, type IV collagen and laminin

Megakaryocytes associate with the bone marrow vasculature where they convert their cytoplasm into proplatelets that protrude through the vascular endothelium into the lumen and release platelets. The extracellular matrix (ECM) microenvironment plays a critical role in regulating these processes. In...

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Detalles Bibliográficos
Main Authors: Malara, Alessandro, Currao, Manuela, Gruppi, Cristian, Celesti, Giuseppe, Viarengo, Gianluca, Buracchi, Chiara, Laghi, Luigi, Kaplan, David L., Balduini, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096110/
https://ncbi.nlm.nih.gov/pubmed/24357118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1626
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