Megakaryocytes contribute to the bone marrow-matrix environment by expressing fibronectin, type IV collagen and laminin

Megakaryocytes associate with the bone marrow vasculature where they convert their cytoplasm into proplatelets that protrude through the vascular endothelium into the lumen and release platelets. The extracellular matrix (ECM) microenvironment plays a critical role in regulating these processes. In...

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Bibliographic Details
Main Authors: Malara, Alessandro, Currao, Manuela, Gruppi, Cristian, Celesti, Giuseppe, Viarengo, Gianluca, Buracchi, Chiara, Laghi, Luigi, Kaplan, David L., Balduini, Alessandra
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096110/
https://ncbi.nlm.nih.gov/pubmed/24357118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1626
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