Megakaryocytes contribute to the bone marrow-matrix environment by expressing fibronectin, type IV collagen and laminin

Megakaryocytes associate with the bone marrow vasculature where they convert their cytoplasm into proplatelets that protrude through the vascular endothelium into the lumen and release platelets. The extracellular matrix (ECM) microenvironment plays a critical role in regulating these processes. In...

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Main Authors: Malara, Alessandro, Currao, Manuela, Gruppi, Cristian, Celesti, Giuseppe, Viarengo, Gianluca, Buracchi, Chiara, Laghi, Luigi, Kaplan, David L., Balduini, Alessandra
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096110/
https://ncbi.nlm.nih.gov/pubmed/24357118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1626
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