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Phase I/II trial design when response is unobserved in subjects with dose-limiting toxicity
We propose a Phase I/II trial design in which subjects with dose-limiting toxicity are not followed for response, leading to three possible outcomes for each subject: dose-limiting toxicity, absence of therapeutic response without dose-limiting toxicity, and presence of therapeutic response without...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096077/ https://ncbi.nlm.nih.gov/pubmed/23117408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280212464541 |
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