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Structure-Guided Transformation of Channelrhodopsin into a Light-Activated Chloride Channel
Using light to silence electrical activity in targeted cells is a major goal of optogenetics. Available optogenetic proteins that directly move ions to achieve silencing are inefficient, pumping only a single ion per photon across the cell membrane rather than allowing many ions per photon to flow t...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096039/ https://ncbi.nlm.nih.gov/pubmed/24763591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1252367 |
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