Genetic transfer of a nonpeptide antagonist binding site to a previously unresponsive angiotensin receptor.
Mutational analysis based on the pharmacological differences between mammalian and amphibian angiotensin II receptors (AT receptors) previously identified 7 aa residues located in transmembrane domains (TMs) III (Val-108), IV (Ala-163), V (Pro-192, Thr-198), VI (Ser-252), and VII (Leu-300, Phe-301)...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1995
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.20.9240 |
| Oznake: |
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