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A new insect cell glycoengineering approach provides baculovirus-inducible glycogene expression and increases human-type glycosylation efficiency

Insect cells are often glycoengineered using DNA constructs encoding foreign glyocoenzymes under the transcriptional control of the baculovirus immediate early promoter, ie1. However, we recently found that the delayed early baculovirus promoter, 39K, provides inducible and higher levels of transgen...

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Détails bibliographiques
Auteurs principaux: Toth, Ann M., Kuo, Chu-Wei, Khoo, Kay-Hooi, Jarvis, Donald L.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095979/
https://ncbi.nlm.nih.gov/pubmed/24768688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2014.04.011
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