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A new insect cell glycoengineering approach provides baculovirus-inducible glycogene expression and increases human-type glycosylation efficiency

Insect cells are often glycoengineered using DNA constructs encoding foreign glyocoenzymes under the transcriptional control of the baculovirus immediate early promoter, ie1. However, we recently found that the delayed early baculovirus promoter, 39K, provides inducible and higher levels of transgen...

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Detalhes bibliográficos
Main Authors: Toth, Ann M., Kuo, Chu-Wei, Khoo, Kay-Hooi, Jarvis, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095979/
https://ncbi.nlm.nih.gov/pubmed/24768688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2014.04.011
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