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Resistance of Cancer Cells to Targeted Therapies Through the Activation of Compensating Signaling Loops

The emergence of low molecular weight kinase inhibitors as “targeted” drugs has led to remarkable advances in the treatment of cancer patients. The clinical benefits of these tumor therapies, however, vary widely in patient populations and with duration of treatment. Intrinsic and acquired resistanc...

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Autors principals: von Manstein, Viktoria, Yang, Chul Min, Richter, Diane, Delis, Natalia, Vafaizadeh, Vida, Groner, Bernd
Format: Artigo
Idioma:Inglês
Publicat: Bentham Science Publishers 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095943/
https://ncbi.nlm.nih.gov/pubmed/25045345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1574362409666140206221931
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