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Resistance of Cancer Cells to Targeted Therapies Through the Activation of Compensating Signaling Loops

The emergence of low molecular weight kinase inhibitors as “targeted” drugs has led to remarkable advances in the treatment of cancer patients. The clinical benefits of these tumor therapies, however, vary widely in patient populations and with duration of treatment. Intrinsic and acquired resistanc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: von Manstein, Viktoria, Yang, Chul Min, Richter, Diane, Delis, Natalia, Vafaizadeh, Vida, Groner, Bernd
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Science Publishers 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095943/
https://ncbi.nlm.nih.gov/pubmed/25045345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1574362409666140206221931
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