Neuronal IκB Kinase β Protects Mice from Autoimmune Encephalomyelitis by Mediating Neuroprotective and Immunosuppressive Effects in the Central Nervous System()

Some aspects of CNS-directed autoimmunity in multiple sclerosis are modeled in mice by immunization with myelin Ags where tissue damage is driven by myelin-reactive Th1 and Th17 effector lymphocytes. Whether the CNS plays an active role in controlling such autoimmune diseases is unknown. We used mic...

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Main Authors: Emmanouil, Mary, Taoufik, Era, Tseveleki, Vivian, Vamvakas, Sotiris-Spyros, Tselios, Theodore, Karin, Michael, Lassmann, Hans, Probert, Lesley
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095798/
https://ncbi.nlm.nih.gov/pubmed/20007573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900834
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