Rational Design and Synthesis of Altered Peptide Ligands based on Human Myelin Oligodendrocyte Glycoprotein 35–55 Epitope: Inhibition of Chronic Experimental Autoimmune Encephalomyelitis in Mice

Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease of the central nervous system and is an animal model of multiple sclerosis (MS). Although the etiology of MS remains unclear, there is evidence T-cell recognition of immunodominant epitopes of myelin proteins, such as the 35–...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Tselios, Theodore, Aggelidakis, Mihalis, Tapeinou, Anthi, Tseveleki, Vivian, Kanistras, Ioannis, Gatos, Dimitrios, Matsoukas, John
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270842/
https://ncbi.nlm.nih.gov/pubmed/25375337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191117968
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker