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Inhibition of Cathepsin Activity in a Cell-Based Assay by a Light-Activated Ruthenium Compound
Light-activated inhibition of cathepsin activity was demonstrated with in a cell-based assay. Inhibitors of cathepsin K, Cbz-Leu-NHCH(2)CN (2) and Cbz-Leu-Ser(OBn)-CN (3), were caged within the complexes cis-[Ru(bpy)(2)(2)(2)]Cl(2) (4) and cis-[Ru(bpy)(2)(3)(2)](BF(4))(2) (5), where bpy = 2,2′-bipyr...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4095795/ https://ncbi.nlm.nih.gov/pubmed/24729544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201400081 |
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