Role of the Adjacent Stroma Cells in Prostate Cancer Development and Progression: Synergy between TGF-β and IGF Signaling

This review postulates the role of transforming growth factor-beta (TGF-β) and insulin-like growth factor (IGF-I/IGF-II) signaling in stromal cells during prostate carcinogenesis and progression. It is known that stromal cells have a reciprocal relationship to the adjacent epithelial cells in the ma...

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Bibliographic Details
Main Authors: Lee, Chung, Jia, Zhenyu, Rahmatpanah, Farah, Zhang, Qiang, Zi, Xiaolin, McClelland, Michael, Mercola, Dan
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095744/
https://ncbi.nlm.nih.gov/pubmed/25089270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/502093
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