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Variable recombination dynamics during the emergence, transmission and ‘disarming’ of a multidrug-resistant pneumococcal clone

BACKGROUND: Pneumococcal β-lactam resistance was first detected in Iceland in the late 1980s, and subsequently peaked at almost 25% of clinical isolates in the mid-1990s largely due to the spread of the internationally-disseminated multidrug-resistant PMEN2 (or Spain(6B)-2) clone of Streptococcus pn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Croucher, Nicholas J, Hanage, William P, Harris, Simon R, McGee, Lesley, van der Linden, Mark, de Lencastre, Herminia, Sá-Leão, Raquel, Song, Jae-Hoon, Ko, Kwan Soo, Beall, Bernard, Klugman, Keith P, Parkhill, Julian, Tomasz, Alexander, Kristinsson, Karl G, Bentley, Stephen D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094930/
https://ncbi.nlm.nih.gov/pubmed/24957517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-12-49
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