A classification and characterization of two-locus, pure, strict, epistatic models for simulation and detection

BACKGROUND: The statistical genetics phenomenon of epistasis is widely acknowledged to confound disease etiology. In order to evaluate strategies for detecting these complex multi-locus disease associations, simulation studies are required. The development of the GAMETES software for the generation...

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Detaylı Bibliyografya
Asıl Yazarlar: Urbanowicz, Ryan J, Granizo-Mackenzie, Ambrose LS, Kiralis, Jeff, Moore, Jason H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094921/
https://ncbi.nlm.nih.gov/pubmed/25057293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-7-8
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