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Predicting the difficulty of pure, strict, epistatic models: metrics for simulated model selection

BACKGROUND: Algorithms designed to detect complex genetic disease associations are initially evaluated using simulated datasets. Typical evaluations vary constraints that influence the correct detection of underlying models (i.e. number of loci, heritability, and minor allele frequency). Such studie...

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Detalhes bibliográficos
Main Authors: Urbanowicz, Ryan J, Kiralis, Jeff, Fisher, Jonathan M, Moore, Jason H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549792/
https://ncbi.nlm.nih.gov/pubmed/23014095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-5-15
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