Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar Aβ (1–42) to the Rat Brain

Several animal models of Alzheimer's disease have been used in laboratory experiments. Intrahippocampal injection of fibrillar amyloid-beta (fAβ) peptide represents one of the most frequently used models, mimicking Aβ deposits in the brain. In our experiment synthetic fAβ (1–42) peptide was adm...

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Hauptverfasser: Borbély, Emőke, Horváth, János, Furdan, Szabina, Bozsó, Zsolt, Penke, Botond, Fülöp, Lívia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094878/
https://ncbi.nlm.nih.gov/pubmed/25050342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/345305
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