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Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite

Gene expression and metabolism are coupled at numerous levels. Cells must sense and respond to nutrients in their environment, and specialized cells must synthesize metabolic products required for their function. Pluripotent stem cells have the ability to differentiate into a wide variety of special...

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Détails bibliographiques
Auteurs principaux: Clingman, Carina C, Deveau, Laura M, Hay, Samantha A, Genga, Ryan M, Shandilya, Shivender MD, Massi, Francesca, Ryder, Sean P
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094780/
https://ncbi.nlm.nih.gov/pubmed/24935936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02848
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