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Therapeutic suppression of premature termination codons: Mechanisms and clinical considerations (Review)

An estimated one-third of genetic disorders are the result of mutations that generate premature termination codons (PTCs) within protein coding genes. These disorders are phenotypically diverse and consist of diseases that affect both young and old individuals. Various small molecules have been iden...

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Hlavní autoři: KARIJOLICH, JOHN, YU, YI-TAO
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094583/
https://ncbi.nlm.nih.gov/pubmed/24939317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2014.1809
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