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Spliceozymes: Ribozymes that Remove Introns from Pre-mRNAs in Trans

Group I introns are pre-mRNA introns that do not require the spliceosome for their removal. Instead, they fold into complex three-dimensional structures and catalyze two transesterification reactions, thereby excising themselves and joining the flanking exons. These catalytic RNAs (ribozymes) have b...

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Autores principales: Amini, Zhaleh N., Olson, Karen E., Müller, Ulrich F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094466/
https://ncbi.nlm.nih.gov/pubmed/25014025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101932
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