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Prediction of kinase inhibitor response using activity profiling, in vitro screening, and elastic net regression
BACKGROUND: Many kinase inhibitors have been approved as cancer therapies. Recently, libraries of kinase inhibitors have been extensively profiled, thus providing a map of the strength of action of each compound on a large number of its targets. These profiled libraries define drug-kinase networks t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4094402/ https://ncbi.nlm.nih.gov/pubmed/24961498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-74 |
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