Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion.

Vinculin, a major constituent of focal adhesions and zonula adherens junctions, is thought to be involved in linking the microfilaments to areas of cell-substrate and cell-cell contacts. To test the role of vinculin in cell adhesion and motility, we used homologous recombination to generate F9 embry...

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Detalhes bibliográficos
Main Authors: Coll, J L, Ben-Ze'ev, A, Ezzell, R M, Rodríguez Fernández, J L, Baribault, H, Oshima, R G, Adamson, E D
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC40944/
https://ncbi.nlm.nih.gov/pubmed/7568093
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