Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion.

Vinculin, a major constituent of focal adhesions and zonula adherens junctions, is thought to be involved in linking the microfilaments to areas of cell-substrate and cell-cell contacts. To test the role of vinculin in cell adhesion and motility, we used homologous recombination to generate F9 embry...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Coll, J L, Ben-Ze'ev, A, Ezzell, R M, Rodríguez Fernández, J L, Baribault, H, Oshima, R G, Adamson, E D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40944/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.20.9161
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