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Pathogenetic Importance and Therapeutic Implications of NF-κB in Lymphoid Malignancies

Derangement of the nuclear factor κB (NF-κB) pathway initiates and/or sustains many types of human cancer. B-cell malignancies are particularly affected by oncogenic mutations, translocations, and copy number alterations affecting key components the NF-κB pathway, most likely owing to the pervasive...

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Detalhes bibliográficos
Main Authors: Lim, Kian-Huat, Yang, Yibin, Staudt, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094296/
https://ncbi.nlm.nih.gov/pubmed/22435566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2012.01105.x
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