Attenuated adipose tissue and skeletal muscle inflammation in obese mice with combined CD4+ and CD8+ T cell deficiency

OBJECTIVES: High-fat diet (HFD) feeding in mice is characterized by accumulation of αβ T cells in adipose tissue. However, the contribution of αβ T cells to obesity-induced inflammation of skeletal muscle, a major organ of glucose uptake, is unknown. This study was undertaken to evaluate the effect...

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Main Authors: Khan, Ilvira M., Perrard, Xiao-Yuan Dai, Perrard, Jerry L., Mansoori, Amir, Smith, C. Wayne, Wu, Huaizhu, Ballantyne, Christie M.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094239/
https://ncbi.nlm.nih.gov/pubmed/24530773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2014.01.011
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