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Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination
Inherited mutations in human PALB2 are associated with a predisposition to breast and pancreatic cancers. The tumor-suppressing capability of PALB2 is thought to be based on its ability to enable BRCA2 function in homologous recombination. However, the biochemical properties of PALB2 are unknown. He...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4094107/ https://ncbi.nlm.nih.gov/pubmed/20871615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1915 |
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