Phosphorylation of the Transcription Activator CLOCK Regulates Progression through a ∼24-h Feedback Loop to Influence the Circadian Period in Drosophila

Circadian (≅24 h) clocks control daily rhythms in metabolism, physiology, and behavior in animals, plants, and microbes. In Drosophila, these clocks keep circadian time via transcriptional feedback loops in which CLOCK-CYCLE (CLK-CYC) initiates transcription of period (per) and timeless (tim), accum...

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Detalhes bibliográficos
Main Authors: Mahesh, Guruswamy, Jeong, EunHee, Ng, Fanny S., Liu, Yixiao, Gunawardhana, Kushan, Houl, Jerry H., Yildirim, Evrim, Amunugama, Ravi, Jones, Richard, Allen, David L., Edery, Isaac, Kim, Eun Young, Hardin, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094078/
https://ncbi.nlm.nih.gov/pubmed/24872414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568493
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