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Opioid Receptor Function Is Regulated by Post-endocytic Peptide Processing

Most neuroendocrine peptides are generated in the secretory compartment by proteolysis of the precursors at classical cleavage sites consisting of basic residues by well studied endopeptidases belonging to the subtilisin superfamily. In contrast, a subset of bioactive peptides is generated by proces...

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Autori principali: Gupta, Achla, Gomes, Ivone, Wardman, Jonathan, Devi, Lakshmi A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094072/
https://ncbi.nlm.nih.gov/pubmed/24847082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537704
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